最近加入的商品:

    0 件商品 合计 0

    配套服务

    立足于生命科学,为基础研究领域科学工作者提供生物学高端技术服务

    undefined
    +
    • undefined

    MYC-Scfv

    零售价

    ¥ 280

    品牌: 南京瑞源生物 名称: myc ScFv 货号: RY-K9004 品类: 蛋白制品

    产品货号: RY-K9004

    • 规格
      • 400ul
      • 50ul
    数量
    -
    +

    库存剩余

    1998

    隐藏域元素占位

    产品描述 说明书

    ▼ 产品规格

    产品名称

     货号  规格

    MYC-ScFv

    RY-K9004-50ul

    50ul

    RY-K9004-400ul

    400ul

     

    Background:

    C-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Myc proteins are nuclear proteins with relatively short half lives. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas. The L-Myc gene has been reported to be amplified and expressed at high level in human small cell lung carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif (bHLH-Zip) protein, designated Max, specifically associates with c-Myc, N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibit appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins, Mad and Mxi1, and Mad-Max dimers have been shown to repress transcription through interaction with mSin3.

     

    Specificity:

    Detect c-myc protein.

     

    Storage:

    Store at -20℃. Stable for one year from the date of shipment.

     

    Application:

    WB 1:200-1:2000

     

    Secondary Antibodies:

    Use an anti-Rabbit secondary antibody to detect the ScFv antibody.

    声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!